The Ruesch Center for the Cure of Gastrointestinal Cancers

Good IDEA: Drop Adjuvant Chemo From 6 to 3 Months in CRC
June 12, 2017
Dr John Marshall reports on the practice-changing results of the IDEA study in stage III colorectal cancer looking at duration of adjuvant chemotherapy, as presented at the ASCO plenary session.
John Marshall, MD, and John Neil Primrose, PhD, MBBS, on Biliary Tract Cancer: Results From the BILCAP Trial
June 11, 2017
John Marshall, MD, of Georgetown University, and John Neil Primrose, PhD, MBBS, of the University of Southampton, discuss the potentially practice-changing findings on adjuvant capecitabine for biliary tract cancer. (Abstract 4006)
John Marshall, MD, and Qian Shi, PhD, on Colon Cancer: Results of the IDEA Trial
June 11, 2017
John Marshall, MD, of Georgetown University, and Qian Shi, PhD, of the Mayo Clinic, discuss study findings on shortening the duration of adjuvant oxaliplatin-based therapy, linked to neurotoxicity, for patients with stage III colon cancer. (Abstract LBA1)
ASCO 2017: Impact of Patient Age on Molecular Alterations in Colorectal Tumors
June 7, 2017
Younger patients with colon cancer appear to have more than three times as many mutations in their tumors as older patients, which could lead to more effective treatment decisions, according to researchers at Georgetown Lombardi Comprehensive Cancer Center.
Will Adjuvant Oxaliplatin Data Change Practice in Colon Cancer?
May 26, 2017
Dr John Marshall previews the GI cancer studies being presented at ASCO with his picks for the ones to watch, and predicts that a plenary presentation may be practice-changing.
New finding could lead to more effective treatment decisions for younger colorectal cancer patients
May 18, 2017
Younger colon cancer patients appear to have more than three times as many mutations in their tumors as older patients, which could lead to more effective treatment decisions, say researchers at Georgetown Lombardi Comprehensive Cancer Center.
A Counterintuitive Finding That Could Benefit Younger Colorectal Cancer Patients
May 17, 2017
Younger colon cancer patients appear to have more than three times as many mutations in their tumors as older patients, which could lead to more effective treatment decisions, say researchers at Georgetown Lombardi Comprehensive Cancer Center.
Deficiencies in Repair of DNA Identified in Many Types of Solid Tumors
May 17, 2017
A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.
Caris Life Sciences Appoints John Marshall, M.D., as Chief Medical Officer
May 17, 2017
Caris Life Sciences appoints John Marshall, M.D., as Chief Medical Officer, and will direct research efforts and guide strategies for tumor profiling.
Genomic Findings Reshaping CRC Field
May 16, 2017
Extensive studies into molecular aberrations in colorectal cancer are yielding fresh insights into the potential clinical utility of checkpoint immunotherapies, genetic testing, and tumor-sidedness implications.
The Growing Challenge of Young Adults With Colorectal Cancer
May 15, 2017
In this review, we address specific issues pertaining to AYA patients with colorectal cancer, including evaluation for hereditary colorectal cancer syndromes, clinicopathologic and biologic features unique to AYA patients with colorectal cancer, treatment outcomes, and survivorship.
Health Policy’s Gordian Knot: Rethinking Cost Control
April 26, 2017
Medical spending has resumed its long-term rise. The central, intractable obstacle to long-term cost containment, we contend here, is the near impossibility of saying “no” to ever-more-expensive care that yields small marginal benefits.
Life, Redefined: Living Well With Metastatic Cancer
April 20, 2017
Living well with metastatic cancer means finding ways to accept the diagnoses and continue to move forward.
A Diagnosis No Young Person Expects
April 18, 2017
Matt Wixon was 39 years old and preparing for the birth of his first child when he was diagnosed with stage 4 colon cancer. While rates of colon cancer are declining among older adults, they are on the rise in people under age 50 - a troubling trend.

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